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Three Substances as Known to Cause Cancer were Added to California 65 Chemicals List Release Time:2023-02-01

On January 27, 2023, the Office of Environmental Health Hazard Assessment (OEHHA) issued a notice to update the California 65 Chemicals List. 1-bromo-3-chloropropane, 1-butyl glycidyl ether, and glycidyl methacrylate were listed in the California 65 Chemicals List due to cause cancer.

According to California Proposition 65, if the product contains added substances after the substances are listed, clear and reasonable warning signs shall be provided within one year, that is, the warning must be completed before January 27, 2024.



Type of Toxicity

Main Usage




As an industrial intermediate for the production of other chemicals.

1-butyl glycidyl ether



Used in adhesives and sealants, coating products and fillers, putties, plasters, modelling;

Used as a reactive diluent in epoxy resins, and as an acid acceptor for

stabilizing chlorinated solvents and chemical intermediates

glycidyl methacrylate



Used in polymers and coating products

As an industrial intermediate for the production of other chemicals.

California 65 List is a list of chemicals known to cause cancer, reproductive system or other cumulative toxicity published by California and updated annually. This list, which must be updated at least once a year, has grown to include approximately 1000 chemicals since it was first published in 1987. California 65 does not set limits for hazardous substances in products, but can refer to existing litigation cases or agreements for relevant categories of products. Enterprises need to pay attention to the use of the chemicals in the list in products, especially the substances involved in previous cases and the new chemicals added by the list, and carry out supply chain investigations for these high-risk chemical substances, which can be tested if necessary.

Products containing the listed chemicals are required to affix warning signs according to the specified requirements, otherwise it may face lawsuits and huge fines. AGC can provide specific solutions for products to respond to California 65, selectively screen California 65 controlled substances for products and materials used to help enterprises cope with environmental impact.

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